Dr. Scott Tebbutt is Chief Scientific Officer for the Prevention of Organ Failure (PROOF) Centre of Excellence, and Professor in the Department of Medicine, Division of Respiratory Medicine, University of British Columbia. He is also a Principal Investigator at the UBC Centre for Heart Lung Innovation (HLI), St. Paul’s Hospital, Vancouver, Canada. Since 2006, he has served as Co-Director of the Molecular Phenotyping and Genotyping Core of the HLI, and he is currently Director of the Technology Development Core. Dr. Tebbutt earned his B.A. degree in Biochemistry from the University of Oxford (Oriel College), England in 1989 and his Ph.D. in Molecular Genetics from the University of East Anglia (Cambridge Laboratory, John Innes Centre, England) in 1993. He pursued post-doctoral fellowships in the laboratories of Professor Ann Harris (University of Oxford, Institute of Molecular Medicine) and Professor Diana Hill (University of Otago, Dunedin, New Zealand), where he studied the molecular genetics of cystic fibrosis. He was appointed Research Fellow at the University of Otago (1995-2001), leading a research team investigating the genomics of the sheep cystic fibrosis locus. He was seconded to a start-up biotechnology company (Global Technologies (NZ) Ltd.) as Director of Genomics (1999-2001). He moved to Canada in 2001, and was Senior Researcher in the Centre for Biomedical Research (University of Victoria, 2001-2002), prior to being recruited to the UBC HLI (formerly James Hogg Research Centre) at St. Paul’s Hospital, Vancouver (2002).
Dr. Tebbutt’s research program is focused on the genomics of complex respiratory disease, including the early and late reactions in allergic asthma. He also leads a multidisciplinary collaboration to investigate interactions between fungal spores and human airway cells. His research combines hypothesis-driven study of biological mechanisms with the development of advanced tools and ‘OMICs’ technology (including bioinformatics and computational biology for data integration) to better facilitate basic and translational research. Dr. Tebbutt has published original research contributions in journals such as the Proceedings of the National Academy of Sciences (U.S.A.), American Journal of Respiratory and Critical Care Medicine, Journal of Immunology, Journal of Medical Genetics, Genomics, BioTechniques, BioinfoOrmatics and Public Library of Science (PLOS). He has published numerous technical reviews as well as book chapters on the role of genetic variation in respiratory disease. He has served as reviewer on several grant panels, including the Canadian Institutes of Health Research and the Michael Smith Foundation for Health Research, and he is Associate Editor for the journal BMC Genetics.
Dr. Tebbutt has received several fellowships and awards, including an Edward Penley Abraham Research Trust Fellowship (U.K.), a Journal of Cell Science Traveling Fellowship Award, and a Research Fellowship from the Cystic Fibrosis Association of New Zealand. He has been awarded competitive research funding from organizations such as the National Sanitarium Association (Canada), the British Columbia Lung Association, AllerGen NCE Inc. (Allergy, Genes and Environment Network), the Canadian Institutes of Health Research, the Natural Sciences and Engineering Research Council, the National Institute of Allergy and Infectious Disease (USA) and the Wellcome Trust (U.K.).